Alpha Genesis offers advanced spinal research models designed to evaluate therapies and devices targeting degenerative disc disease, spinal cord injury, and vertebral repair under clinically relevant conditions. Our capabilities include cervical and lumbar disc access, intervertebral injections, vertebral stabilization, and implant evaluations, each performed with high-resolution imaging support and surgical precision to ensure reproducibility. Studies can incorporate regenerative scaffolds, biologics, gene therapy vectors, and next-generation implants, all tested under dynamic loading and biomechanical stress conditions that mirror clinical environments. Imaging modalities such as MRI, CT, and fluoroscopy are used longitudinally to assess disc height, hydration status, structural repair, and integration of implants, while histology, immunohistochemistry, and biomarker panels provide cellular- and tissue-level insights into inflammatory response, fibrosis, and regeneration.

 

Safety and efficacy data are collected across acute and long-term phases, enabling comprehensive evaluation of therapeutic durability and tolerability. Experienced neurosurgical teams ensure precise delivery and perioperative care, while strict GLP compliance and AAALAC oversight guarantee regulatory readiness and data integrity. By combining advanced procedural expertise, imaging integration, and multiparametric functional outcomes, our spinal platforms generate high-value datasets that guide translational development, support regulatory submissions, and enable the responsible advancement of therapies designed to address debilitating spinal conditions.