Pharmaceutical & Biopharmaceutical Companies
Drug developers requiring NHP safety pharmacology, toxicology, PK/PD, and IND-enabling study support for small molecules, biologics, and advanced therapeutics, with GLP-aligned documentation available.
Research animal retirement and lifetime care, now available through Alpha Genesis. Professionally managed lifetime care for retired research primates, with expert social reintroduction into stable outdoor groups led by veterinary staff deeply experienced in laboratory-animal medicine.
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Translational NHP studies for pharmaceutical, biotechnology, academic, and government sponsors, from early non-GLP pharmacology through GLP IND-enabling toxicology, led by board-certified veterinarians and decades of primate expertise.
NHP research provides translational insights that are often critical to the advancement of vaccines, biologics, infectious disease countermeasures, and complex therapeutics. Alpha Genesis brings decades of operational experience in NHP colony management, study execution, and health program development to support the full spectrum of preclinical NHP research, from early pharmacology and biomarker profiling through safety pharmacology, repeat-dose toxicology, and large-scale government biodefense programs.
NHP capabilities span pharmacokinetics and pharmacodynamics, dose-ranging and tolerability, acute and repeat-dose toxicology, vaccine immunogenicity, infectious-disease models, immunology and biomarker work, reproductive and developmental studies, neuroscience, surgical and interventional models, and custom sponsor-defined protocols. GLP and non-GLP study support is available, with IND-enabling study design and GLP-aligned documentation matched to your regulatory strategy.
Exceptional primate care is what sets NHP data apart. Decades of colony management, board-certified laboratory-animal veterinary leadership, and experienced animal-care teams support social housing, environmental enrichment, behavioral management, and positive-reinforcement training that keep animals behaviorally and physiologically stable. Operating under IACUC oversight and backed by AAALAC accreditation, USDA registration, and OLAW Assurance, that care is not box-checking; healthy, stable animals are what make the data reliable.
Drug developers requiring NHP safety pharmacology, toxicology, PK/PD, and IND-enabling study support for small molecules, biologics, and advanced therapeutics, with GLP-aligned documentation available.
Organizations developing prophylactic and therapeutic vaccines, monoclonal antibodies, and immune-modulating therapies that rely on NHP immunological and virological models for preclinical validation.
Federal and defense research programs, including BARDA, NIH, and DoD-sponsored efforts, requiring experienced NHP study execution for infectious disease countermeasures, biodefense models, and large-scale immunological assessments.
University and consortium investigators conducting NIH-funded NHP research in neuroscience, reproductive biology, immunology, and behavioral sciences who require compliant animal care, technical expertise, and study coordination support.
Contract research organizations and multi-site research consortia seeking a reliable NHP partner for co-execution, overflow capacity, or specialized species and model access.
Our NHP preclinical platform covers a wide range of in vivo study types, available for research clients and matched to your protocol, species, and timeline.
Alpha Genesis maintains established colonies of multiple NHP species commonly used in translational preclinical research.
The most widely used NHP in preclinical research, with well-characterized immunological profiles, physiological similarity to humans, and extensive historical datasets across pharmacology, toxicology, vaccines, infectious disease, and neuroscience applications.
Frequently selected for pharmaceutical safety pharmacology, repeat-dose toxicology, and biologic development programs. Cynomolgus macaques are a primary NHP species in IND-enabling regulatory studies and are commonly required by regulatory agency guidance for specific therapeutic modalities.
A distinctive NHP model with particular relevance to infectious disease, biodefense, respiratory disease, and select virological research programs. Alpha Genesis maintains an established African green monkey program and operational experience with this species that is not widely available at other CROs.
Available for select neuroscience, behavioral, and specialized NHP research programs, supported by experienced veterinary and husbandry teams.
Beyond our core species, Alpha Genesis can and has supported additional NHP models, including spider monkeys, pigtail macaques, baboons, and marmosets, through custom programs. Talk to us about translational model fit for your study.
NHP study execution draws on experienced technical, veterinary, and scientific teams with well-established SOPs for all major study activities.
NHP study quality at Alpha Genesis is built on decades of primate expertise. Board-certified laboratory-animal veterinarians provide medical direction, clinical monitoring, and preventive health management throughout study conduct, supported by experienced veterinary technicians and animal-care teams. Species-specific enrichment, behavioral management, positive-reinforcement training, and social housing keep animals study-ready, while SOP-driven operations and complete documentation keep programs ready for sponsor and regulatory inspection. The program operates under a federally recognized animal-care and compliance framework, including AAALAC accreditation, USDA registration, OLAW Assurance, and IACUC oversight, and supports both GLP and non-GLP work. Our quality systems follow internationally recognized GLP expectations, and we routinely generate data that supports submissions to major health authorities, including the FDA, EMA, MHRA, and PMDA, where appropriate.
Veterinarian-led, enrichment-rich NHP care at Alpha Genesis, grounded in decades of primate expertise and AAALAC accreditation, produces animals with stable social structures, natural behavioral repertoires, and consistent physiological baselines. Compliance is expected; this depth of care is what makes the resulting data reproducible.
Decades of NHP colony management, veterinary health program development, and study execution across multiple species have built institutional depth that informs every aspect of study design, animal handling, and data collection.
Board-certified laboratory-animal veterinarians provide continuous medical oversight, from protocol feasibility review through terminal procedures. Veterinary judgment is embedded in study conduct, not consulted only at problem points.
NHP study teams work directly with sponsor scientists and project managers, providing science-grounded responses to feasibility questions, protocol amendments, and data interpretation discussions.
Alpha Genesis has supported government-sponsored biodefense, infectious disease, and vaccine programs requiring large cohorts, complex multi-arm designs, and stringent regulatory documentation. This experience translates to reliable execution of demanding commercial and academic programs.
Sponsors across the United States, Europe, and Asia rely on Alpha Genesis for translational NHP work. Dedicated project managers, worldwide sample shipping, and secure electronic data transfer keep cross-border programs running smoothly, with data built to fit a global regulatory strategy.
We support preclinical research in rhesus macaques, cynomolgus macaques, African green monkeys, and capuchins, with custom programs available for additional species on request. Species selection should be driven by scientific rationale, compound pharmacology, and regulatory guidance. Our scientific teams can assist with species selection discussions.
Contact our scientific and business development teams to discuss species availability, study feasibility, protocol requirements, and timeline for your NHP preclinical program.